nicotinic acid CAS 59-67-6, nicotinic acid CAS 59-67-6
In today's rich and colorful world of chemical substances, there is a substance that attracts much attention - niacin. It has several well-known names, among which the names of vitamin B3 and vitamin PP are particularly deeply rooted in people's minds. Niacin has a unique physical property, which is heat resistance.
59-67-6
C6H5NO2
123.11
200-441-0
Chemical Name | Nicotinic Acid |
Other Name | Nicotinic acid powder; Vitamin B3; Vitamin PP; Nicotinic |
CAS | 59-67-6 |
EINECS | 200-441-0 |
Type | Food additives; Feed additives; Pharmaceutical raw materials; Flavors and fragrances; Pharmaceuticals, pesticides, dye intermediates |
Molecular Formula | C6H5NO2 |
Molecular Weight | 123.11 |
Melting point | 236-239 °C(lit.) |
Boiling point | 260C |
density | 1.473 |
refractive index | 1.5423 (estimate) |
Fp | 193°C |
storage temp. | 2-8°C |
solubility | 18g/l |
pka | 4.85(at 25℃) |
form | Powder |
color | White to off-white |
PH | 2.7 (18g/l, H2O, 20℃) |
Water Solubility | 1-5 g/100 mL at 17 ºC |
Stability: | Stable. Incompatible with strong oxidizing agents. May be light sensitive. |
In today's rich and colorful world of chemical substances, there is a substance that attracts much attention - niacin. It has several well-known names, among which the names of vitamin B3 and vitamin PP are particularly deeply rooted in people's minds. Niacin has a unique physical property, which is heat resistance. Even in a relatively high-temperature environment, it can still maintain the relative stability of its structure and will not easily undergo changes such as denaturation or decomposition. Moreover, it also has the ability to sublimate. Under certain conditions, it can directly transform from a solid state to a gaseous state. This characteristic makes it demonstrate unique advantages in specific application scenarios.
It is worth mentioning that niacin has another meaningful alternative name - "anti-peace element", as if suggesting that it plays an indispensable role in maintaining the health balance of the human body. In the human body, the situation is more complex and delicate. Besides niacin itself, there are also its corresponding acquired substances, namely nicotinamide or related forms of nicotinamide. As one of the 13 essential vitamins for the human body, it shoulders the important mission of maintaining the normal physiological functions of the human body.
From a chemical perspective, niacin is a water-soluble vitamin, which means it can dissolve in water and in the body's fluid environment, it can be transported to various places where it is needed through physiological processes such as blood circulation to play its role. At the same time, it is also a member of the vast family of B vitamins, working in concert with other B vitamins to jointly safeguard human health.
Niacin plays a crucial physiological role in the human body. It can be interconverted with nicotinamide and ingeniously participates in coenzymes and the synthesis process of coenzymes. This process is like a precise relay race of chemical reactions, in which niacin plays a crucial role as a transmitter, ensuring that many biochemical reactions in the body can proceed smoothly. Moreover, niacin plays an indispensable role in regulating the lipid metabolism rate within the body, maintaining the respiratory oxidation process of tissues, and anaerobic decomposition of carbohydrates, among other key physiological links. It is like a silent guardian commander, precisely regulating the metabolic order within the body.
From a biochemical perspective, we will find that niacin is actually the precursor substance of coenzymes NAD and NADP. In nature, it presents a relatively scattered state of existence, as if nature deliberately hides it in every corner, waiting for people to discover and utilize it. However, it is not hard to find. In some common foods, such as liver, which is the "nutrition warehouse" of the human body, there is a large amount of niacin. In addition, nutrient-rich fish, tiny yeasts and various grains all contain abundant niacin resources, supplementing this important nutrient for the human body.
Interestingly, in terms of diet, if the intake of niacin in the human body is insufficient, it will be associated with a disease called pellagra. This warns us how important it is to ensure adequate intake of niacin for maintaining good health. In addition, in the application of chemical terms, the concept of "niacin" is often extended to refer to nicotinamide or other derivatives with the organic activity of niacin. After all, they are closely related in chemical properties and physiological functions and all belong to the large category of substances such as vitamins (enzyme cofactors).
Looking at the current application fields, niacin can be said to have shown its prowess. At present, it is widely used as a feed additive and plays a key role in industries such as livestock breeding. When added to the feed, it is like injecting a magical power into the animals' diet, significantly enhancing the utilization value of healthy proteins in the feed, enabling the animals to better absorb and utilize these nutrients, and thus thrive. For example, for dairy cows, niacin can help them increase milk production and bring more economic benefits to farmers. For various livestock and poultry such as fish, chickens, ducks, livestock and sheep, niacin can not only increase their output, but also improve the quality of their meat, allowing consumers to enjoy higher-quality food.
In addition to shining brightly in the feed industry, niacin also holds a significant position in the pharmaceutical field. It is a widely used pharmaceutical intermediate, functioning like a bridge connecting basic chemical raw materials with the synthesis processes of various drugs. With the help of nicotinic acid, an important resource, a variety of drugs can be synthesized, such as nicotinamide and nicotinate inositol, etc., contributing to the cause of human health.
Not only that, the application scope of niacin is constantly expanding. In the field of luminescent products, it can participate in the synthesis or modification of luminescent materials by virtue of its unique chemical properties, enabling luminescent products to demonstrate even more outstanding performance. In the dye industry, it can serve as an important auxiliary component to help dyes adhere better to fabrics or endow dyes with brighter and more lasting colors. Even in fine chemical fields such as electroplating, niacin plays an irreplaceable role, assisting in the high-quality electroplating treatment of metal surfaces and endows related products with better appearance and protective performance.
In the complex and delicate tissue structure of the human body, niacin plays a crucial role. As an important hydrogen transporter, it acts like a precise "transporter", methodically participating in the hydrogen transport process within the human body to ensure the smooth operation of each physiological link. Meanwhile, niacin is also a highly effective anti-sepsis factor, playing an indispensable defensive role when the human body resists the severe challenge of sepsis.
From the perspective of maintaining physical health, the role of niacin should not be underestimated. It is like a silent guardian, carefully protecting the health of the skin and nerves. For the skin, niacin can help maintain its normal metabolic function, keeping the skin smooth, delicate, elastic and effectively resisting the damage of the external environment. For the nervous system, it is like a high-quality "lubricating oil", ensuring the accurate transmission of neural signals and maintaining the normal operation of the nervous system. In addition, in the field of digestion, niacin plays a positive promoting role. It can stimulate the secretion of gastric juice and enhance the peristalsis of the gastrointestinal tract, just like injecting a powerful force into the digestive system, helping the human body better absorb and utilize various nutrients.
In the broad research field of biochemistry, niacin is an important tool for exploring the social nutritional composition of tissues. It is like a precise "key" that can help researchers unlock the mystery of the nutritional composition of human tissues and provide key clues for a deeper understanding of the physiological processes of life.
In the field of medical drugs, niacin, as an important member of the vitamin B family, has been widely recognized and applied for its medicinal value. It has demonstrated outstanding ability in the prevention and treatment of diseases. For instance, when dealing with pellagra, a disease caused by niacin deficiency, niacin is undoubtedly one of the most effective "weapons". It can quickly replenish the niacin components needed by the human body, improve skin symptoms and help patients regain their health. Niacin also has a unique therapeutic effect on vascular migraine, a difficult disease. It can relieve vascular spasm and alleviate the pain symptoms of patients by regulating the dilation and contraction function of blood vessels. In addition, niacin often plays an important auxiliary therapeutic role in dealing with various other diseases, bringing a glimmer of hope to patients' recovery.
This product, as a typical vitamin drug, has a specific general term in the medical field - vitamin PP containing nicotinamide. It plays a core role in the treatment of pellagra and is one of the important drugs commonly used in clinical practice. At the same time, due to its special pharmacological properties, it can also be used as a blood dilator, providing sufficient oxygen and nutrients to various tissues and organs of the body by improving blood circulation.
In the food and feed industries, niacin also has extensive applications. It is like a silent and dedicated "nutritionist", being added in large quantities to food and feed as an important additive. In food, niacin can enrich the nutritional components of food, enhance the nutritional value of food, and meet people's demands for a healthy diet. In feed, it provides necessary nutritional support for the growth and development of animals, promoting the healthy development of animal husbandry.
Not only that, niacin also holds a pivotal position in the field of pharmaceutical intermediates. It is a key raw material for the production of many important drugs, such as isoniazid, nicotinamide, nicotinyl and nicotinate inositol, etc. During the process of drug synthesis, niacin is like the "cornerstone" of a building, laying a solid foundation for the birth of these drugs.
In addition to its outstanding performance in the fields of medicine and food, niacin is also an important chemical additive and anti-corrosion agent in the chemical industry. In the special field of photosensitive materials, niacin has demonstrated its unique chemical properties and can be used as an antioxidant and anti-fogging agent. When photosensitive materials are exposed to light, oxidation reactions are prone to occur, leading to a decline in the performance of the materials. The presence of niacin is like a loyal "guardian", effectively resisting the occurrence of oxidation reactions and protecting the stability of photosensitive materials. Meanwhile, it can also act as an anti-fogging agent, preventing fog from forming on the surface of photosensitive materials and affecting their optical performance.
In the electroplating industry, niacin is also a highly favored and powerful additive. In the electroplating solution, even if only 1-10g of niacin is added per liter, a very considerable effect can be produced. It can improve the performance of the electroplating solution, making the coating more uniform and dense, and enhancing the quality and performance of electroplated products.
In the application field of photosensitive products, the role of niacin has also been fully demonstrated. In photosensitive emulsions, simply adding 0.1% niacin liquid can significantly enhance the light safety of photosensitive materials, making them more stable and reliable under light exposure. Adding 5-20 mL of 0.1% niacin water solution to each milliliter of the photosensitive solution can effectively reduce the haze phenomenon produced by the photosensitive product during use, ensuring the clarity and imaging quality of the photosensitive product.