Organic raw material

Methyl niacin appears in the form of crystals or crystalline powder ranging from white to brown in appearance. When people observe carefully, they will find that it has a unique odor characteristic, which is a mixture of fresh scent, caramel-like sweetness, the rich flavor of nuts and a slight tobacco smell. This complex and unique odor makes it have a certain degree of recognition among many chemical substances.

Methyl nicotinate is an irritating substance to human skin. When it comes into contact with human skin, it may cause uncomfortable reactions on the skin. Not only that, it also has a significant dilating effect on blood vessels, enabling them to expand to a certain extent.

In terms of practical application, the main purpose of methyl nicotinate is to be used as a "red additive". When applied to the skin, it will cause redness, swelling or inflammation in the skin within a short period of time. Based on this characteristic, it is often used in lip augmentation or other lip products. Among these products, methyl niacin can achieve the effect of lip augmentation by causing a redness and swelling reaction on the lips, making them look fuller and rosier.

In addition to its application in beauty products, methyl nicotinate is also an active ingredient in many veterinary preparations. In the field of veterinary medicine, it is mainly used for local application and plays the role of a red additive. For example, when treating various animal diseases, it can have positive effects on different conditions. For respiratory system diseases, methyl nicotinate can improve local blood circulation through its vasodilatory effect, which is helpful in alleviating inflammation and discomfort in the respiratory tract. For vascular diseases such as edema and hematoma, it can help relieve the congestion and swelling of blood vessels, promote the absorption of blood and the recovery of circulation. At the same time, when treating rheumatoid diseases in cattle and horses, nicotinate methyl ester can also play a certain role. By improving local blood circulation and metabolism, it can relieve joint pain and inflammation. It should be noted that the concentration of the veterinary drug preparation involved here is 2%, but there are no detailed explanations on other aspects at present.

From the perspective of chemical synthesis, methyl nicotinate is prepared through the esterification reaction of nicotinic acid with methanol in the presence of concentrated sulfuric acid. After the esterification reaction is completed, 10% sodium bicarbonate is used for neutralization treatment to neutralize the remaining acidic substances in the reaction system. Subsequently, through the extraction method, methyl nicotinate was extracted into the organic solvent chloroform, thereby obtaining a relatively pure methyl nicotinate product.

In addition, regarding the research on the DOI synthesis and analgesic activity of methyl nicotinate, the relevant information can be further consulted and understood in the literature "10.4314/ jbp.v12i1.8".

Methyl nicotinate (MN) is a compound used as an active ingredient, and its chemical name is methyl nicotinate. In over-the-counter topical preparations, methyl nicotinate has demonstrated significant redness and anti-irritation effects. This property makes it an effective component for relieving muscle, tendon and joint pain, providing users with temporary relief. It is generally believed that as a reddening agent, the mechanism of action of methyl nicotinate mainly involves the dilation of peripheral blood vessels, and this physiological process is used to achieve the purpose of relieving pain and discomfort.

In the field of veterinary medicine, the application scope of methyl nicotinate is even wider. It is not only used to treat respiratory diseases and help improve the respiratory function of animals; It is also used to treat vascular diseases and promote the health of blood circulation. Meanwhile, for rheumatoid arthritis and diseases such as muscle and joint pain, nicotinate methyl ester has also shown good therapeutic effects, providing a powerful treatment method for veterinary clinical practice.

It is worth noting that methyl nicotinate is not an artificially synthesized compound; it is also widely present in nature. It is reported that methyl niacin can be found in a variety of foods and natural products, such as coffee powder, roasted hazelnuts, guavas, roasted peanuts, wild strawberries, vanilla beans, papayas, guavas, plums, beer cognac, spiny guavas, malt, wort, bourbon vanilla and papayas, etc. These natural sources not only enrich the acquisition routes of methyl nicotinate, but also provide more possibilities for its application in fields such as food and health products.

In addition, methyl nicotinate also plays an important role in the field of chemical synthesis. It can serve as a precursor for synthesis and participate in the preparation process of various complex compounds. For instance, methyl nicotinate can be used as a precursor of the 2-3-pyridinone ligand, which has significant application value in the preparation of derivative coordination polymer chains of silver (I) complexes. Meanwhile, methyl nicotinate can also serve as a precursor for the synthesis of compounds such as 5-aryl nicotinate, ± -cysteine, and 1, 4-dihydropyridine derivatives, providing abundant raw materials and intermediates for the research of organic chemistry and medicinal chemistry.