Trans-4-Dimethylaminocrotonic Acid Hydrochloride cas 848133-35-7-Deshangchemical

Trans-4-Dimethylaminocrotonic Acid Hydrochloride cas 848133-35-7

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English Synonyms:2e)-4-(Dimethylamino)-2-Butenoicacidhydrochloride;afatinibint-2trans-4-Dimethylaminocrotonicacidhydrochloride;2-Butenoicacid,4-(Dimethylamino)-,(2e)-,Hydrochloride;trans-4-Dimethylaminocrotonicacidhydrochloride,>= 97%;trans-4-Dimethylaminocrotonic;trans-4-Dimethylaminocroto

CAS

848133-35-7

Molecular Formula

C6H12ClNO2

Molecular weight

165.62

EINECS

617-631-8

English Synonyms:

2e)-4-(Dimethylamino)-2-Butenoicacidhydrochloride;afatinibint-2trans-4-Dimethylaminocrotonicacidhydrochloride;2-Butenoicacid,4-(Dimethylamino)-,(2e)-,Hydrochloride;trans-4-Dimethylaminocrotonicacidhydrochloride,>= 97%;trans-4-Dimethylaminocrotonic;trans-4-Dimethylaminocrotonicacidhydrochloridesalt;2-Butenoicacid,4-(Dimethylamino)-,Hydrochloride(1:1),(2e)-;trans-4-Dimethylaminocrotonicacidhydrochloride(848133-35-7)

Trans-4-Dimethylaminocroton hydrochloride Chemical Properties

Melting Point	162 °C
Storage conditions	Inert atmosphere,Room Temperature
Solubility	DMSO (a little), methanol (a little), water (a little)
Form	solid
Color	White to off-white
InChI	InChI=1S/C6H11NO2.ClH/c1-7(2)5-3-4-6(8)9;/h3-4H,5H2,1-2H3,(H,8,9);1H/b4-3+;
InChIKey	UUHNQHFOIVLAQX-BJILWQEISA-N
SMILES	C(/CN(C)C)=C\C(=O)O.Cl

Introduction:

Trans-4-dimethylaminocroton hydrochloride is a very important pharmaceutical intermediate. It is an important component of the structure of the anti-tumor drugs afatinib and neratinib.

use:

Trans-4-dimethylaminocroton hydrochloride is a reagent for the preparation of tyrosine kinase inhibitory anti-tumor drugs.

application:

Trans-4-dimethylaminocroton hydrochloride is a carboxylic acid derivative and can be used as a pharmaceutical intermediate.

use:

Organic synthesis intermediates, neratinib intermediates, afatinib intermediates

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