Sodium Salicylate CAS 54-21-7 Information
| CAS |
54-21-7 |
| Molecular formula |
C7H5NaO3 |
| Molecular weight |
160.1 |
| EIENCS |
200-198-0 |
| Form |
Crystals or Crystalline Powder |
| Melting point |
>300 °C (lit.) |
| boling point |
/ |
| Density |
0.32 g/cm3 (20℃) |
| Solubility |
1000g/l |
| PKA |
/ |
| Color |
White |
| Storage temp |
Store at +15°C to +25°C. |
What is Sodium Salicylate CAS 54-21-7?
In the vast world of chemistry, there is a substance called sodium salicylate, whose chemical formula is HOC6H4COONA. From the appearance, it presents a lustrous white powder-like state. Under the illumination of light, that fine powder seems to sparkle with a faint glow, giving people a pure and exquisite feeling.
When we get close to feel it, we will find that it has a wonderful taste. This taste is not the strong and pungent one, but a wonderful flavor that is just right and leaves a lasting impression. At the same time, it also gives off a faint and delicate fragrance. That faint aroma seems to be a unique mark bestowed upon it by nature, gently lingering around, giving people a refreshing feeling.
Sodium salicylate also performs well in terms of solubility. It can dissolve in water and gradually disperse in water to form a uniform solution. It can also dissolve in glycerol and blend with it, showing good compatibility. Similarly, alcohol is also a solvent that it can easily dissolve in. In an alcohol environment, it can dissolve rapidly, as if establishing some kind of tacit cooperative relationship with alcohol.
In the field of medicine, sodium salicylate has important uses. It is often used as a drug and preservative. In medical practice, it plays an indispensable role and safeguards people's health.
So, how is sodium salicylate prepared? This needs to be operated in an aqueous solution environment. First of all, two important raw materials, salicylic acid and sodium bicarbonate, should be prepared in equal molar ratios. When these two substances are added to the aqueous solution, a wonderful chemical reaction will occur between them. During this process, various ions collide and combine with each other under the action of water molecules, gradually forming sodium salicylate.
After the reaction is completed, the next step is evaporation and drying. Through appropriate heating and the removal of moisture, the kind of salt as white as snow that we see was finally obtained, which is sodium salicylate.
However, sodium salicylate also has some interesting properties in its solution state. Especially in the presence of sodium bicarbonate, when the salt is in a static state, it will gradually turn black. This change is like a mysterious "magic" that substances exhibit under specific conditions, making people can't help but marvel at the wonders of the chemical world.
It is worth mentioning that sodium salicylate is the preferred salt for salicylic acid drugs. In practical applications, to alleviate stomach discomfort, it is usually taken together with sodium bicarbonate. This is because sodium bicarbonate can to a certain extent alleviate the irritation of gastric acid on the gastrointestinal tract, making patients feel more comfortable during the process of taking the medicine. In addition, it will also appear in the form of enteric-coated tablets. This special dosage form design enables the drug to be released at specific locations in the intestine, thereby better exerting its efficacy.
However, a key point to note here is that excessive use of sodium bicarbonate is not recommended. Because once the dosage of sodium bicarbonate is inappropriate, it will reduce the level of salicylic acid in the plasma and also increase the excretion of free salicylic acid in the urine. This phenomenon is like a delicate balance being disrupted, which will have a certain impact on the efficacy of drugs and the metabolism of the human body.
In terms of pain relief, although the effect of sodium salicylate is not as significant as that of aspirin, it also has its own unique advantages. It has relatively less irritation to the gastrointestinal tract. For those patients allergic to aspirin, sodium salicylate is undoubtedly a very useful alternative drug. It is like a gentle guardian, alleviating the pain of patients while minimizing the stimulation to their bodies as much as possible, bringing hope and care to those with special constitutions.
Sodium Salicylate CAS 54-21-7 Use
Epidermal relaxant Among numerous chemical substances, sodium salicylate has extensive and important applications. It is ingeniously used to manufacture aspirin, a classic antipyretic and analgesic drug in the medical field, which has relieved the discomfort caused by fever and pain for countless patients. Meanwhile, sodium salicylate is also one of the key raw materials for manufacturing methyl salicylate. Methyl salicylate plays a unique role in multiple fields. For instance, it is often seen in the blending of certain pharmaceutical preparations or fragrances. In addition, it is also involved in the production of various other salicylate salts, which each play an indispensable role in different chemical and pharmaceutical production processes, such as serving as an intermediate in certain chemical reactions or as a component of specific products.
Sodium salicylate is also an azo color coupling agent. In related chemical analysis, detection and some specific industrial production processes, it can undergo specific coupling reactions with azo compounds, thereby achieving the detection, identification or other chemical transformation processes of target substances, providing strong technical support for research and production in related fields.
From a broader perspective, sodium salicylate is an important organic artificial raw material and plays a crucial role in the field of organic synthesis. It is like an important cornerstone for building a complex organic molecular edifice. Through a series of ingenious chemical reactions, it can combine with other organic compounds to generate a wide variety of organic products with specific functions and uses. Meanwhile, as a chemical reagent, sodium salicylate itself also possesses a variety of chemical properties and reaction characteristics, and can play a unique role under specific experimental conditions and production processes, such as participating in the catalysis, regulation or other key steps of certain organic synthesis reactions.
In medical testing, sodium salicylate is an important reagent for determining free acids in gastric juice. By undergoing specific chemical reactions with free acids in gastric juice, the content of free acids in gastric juice can be accurately and sensitively detected. This is of great clinical significance for the diagnosis and research of gastric diseases, helping doctors better understand the health status of patients' stomachs and providing reliable basis for the diagnosis and treatment of diseases.
Not only that, sodium salicylate is also an antipyretic, analgesic and antirheumatic drug. When the human body shows symptoms of fever and pain due to infection, inflammation and other reasons, sodium salicylate can regulate the physiological functions of the human body and act on relevant physiological targets to lower body temperature and relieve pain. For patients with rheumatic diseases, it can help relieve symptoms such as joint pain and swelling, improve the quality of life of patients, and is one of the commonly used drugs in the treatment of rheumatism.
In more specialized fields of microanalysis and chemical research, sodium salicylate is used for microanalysis and the determination of uranium dioxide. In microanalysis, it can have specific reactions with extremely trace amounts of target substances. Through precise detection methods, it can achieve qualitative and quantitative analysis of target substances, providing high-precision detection methods for quality control in scientific research and industrial production. In the determination of uranium dioxide, sodium salicylate, with its unique chemical properties, can form specific chemical complexes or undergo specific chemical reactions with uranium dioxide, thereby accurately determining the content of uranium dioxide. This has significant application value in fields such as the nuclear industry and environmental monitoring.
Meanwhile, sodium salicylate also performs well in the field of organic synthesis. It can participate in various organic synthesis reactions, providing key structural units or reaction intermediates for the synthesis of complex organic molecules, and promoting the development and innovation of organic synthesis chemistry. In addition, sodium salicylate also has antibacterial properties. In some specific antibacterial products or antibacterial treatment plans, it can play a role in inhibiting the growth and reproduction of bacteria, providing an effective chemical means to safeguard human health and prevent bacterial infections.
In medical applications, sodium salicylate is widely used as a painkiller and antipyretic in medicine. When people are troubled by various pains such as headaches, toothaches, and joint pains, or when they have a fever due to diseases like colds and flu, sodium salicylate can relieve pain and lower body temperature by regulating physiological processes such as nerve conduction and inflammatory responses in the human body, helping patients alleviate their physical discomfort. Moreover, salicylate can also be used as a non-steroidal anti-inflammatory drug (NSAID) to cause apoptosis and necrosis of cancer cells. In the research and practice of cancer treatment, scientists have discovered that salicylate can act on specific signaling pathways and metabolic processes of cancer cells, inducing them to initiate self-destructive programs, namely apoptosis, or directly leading to the necrosis of cancer cells, providing a new idea and method for cancer treatment. For those patients who are allergic to aspirin or cannot tolerate its side effects, sodium salicylate is also a potential alternative to aspirin, providing them with another effective treatment option.
In addition, sodium salicylate has a special use, that is, it can be used as a phosphor to detect ultraviolet radiation and electrons in vacuum cleaners. In some specific detection scenarios, by taking advantage of the fluorescence characteristics of sodium salicylate, when it is exposed to ultraviolet radiation or electrons generated by a vacuum cleaner, it will emit a specific fluorescence signal. By detecting this fluorescence signal, it is possible to accurately determine whether there is ultraviolet radiation leakage or electronic-related abnormal conditions in the vacuum cleaner. It provides an effective technical means for product quality inspection and safety guarantee.
