Lysozyme CAS 12650-88-3

Lysozyme CAS 12650-88-3 Information

CAS	12650-88-3
Molecular formula	C125H196N40O36S2
Molecular weight	2899.27014
EIENCS	235-747-3
Form	powder
Melting point	/
boling point	/
Density	/
Solubility	Soluble in water at 10mg/ml.
PKA	/
Color	white
Storage temp	-20°C

What is Lysozyme CAS 12650-88-3?

Molecules and Structure

Molecular weight: Approximately 14.3 - 14.4 kDa (monomeric peptide, containing 129 amino acids).

Structural characteristics: Consists of 4 disulfide bonds for stability, with the N-terminus being lysine and the C-terminus being leucine; has a dual structure domain of α-helix and β-sheet, and the active site contains key amino acids (Glu-35, Asp-52).

Physicochemical properties:

Appearance: White or slightly white freeze-dried powder, slightly sweet, no odor.

Solubility: Easily soluble in water (10 mg/ml), insoluble in acetone and ether.

Stability: Resistant to acid (active retained 87% at 100°C for 45 minutes at pH 3), easily inactivated in alkaline environment; resistant to organic solvent treatment.

Activity conditions

Optimal pH: 5.3 - 6.4 (food preservation), active pH range 6.0 - 9.0.

Optimal temperature: 35°C, maintains high stability at high temperatures (87% activity retained at 96°C for 15 minutes at pH 3).

Lysozyme CAS 12650-88-3 Use

Pharmaceutical field

Indications: Acute and chronic pharyngitis, oral ulcers, chickenpox, herpes zoster, conjunctivitis, etc.

Dosage form and dosage:

Oral lozenges (20mg per tablet): 4-6 times daily.

Enteric-coated tablets (10mg per tablet): 3 times daily, 3-5 tablets each time.

External use: 1-2% solution for instillation or powder spray.

Safety: Occasional mild allergic reactions; the derivative of lysozyme chloride can also be used for expectoration, hemostasis and antiviral purposes.

2. Food industry

Antimicrobial function:

Inhibit Gram-positive bacteria (Bacillus subtilis) and some negative bacteria (Escherichia coli, Proteus mirabilis), with the optimal addition amount of 0.05%.

Complementary formula: When used in combination with phytate, glycine or lactic acid, the effect can be enhanced.

Application scenarios:

Agricultural products (promote the proliferation of bifidobacteria), meat products, aquatic products, baked foods and beverages for preservation.

3. Cosmetics and biotechnology

Cosmetics products:

Toothpaste (prevent dental caries, reduce gum bleeding), mouthwash (addition amount 0.1%).

Skin care products (≤1% addition amount): Improve acne and eczema, such as Gladskin face cream.

Biotechnology:

Prepare protoplasts for genetic engineering or cell fusion.

4. Livestock farming

Alternative to antibiotics: Reduce intestinal diseases in livestock and poultry, improve feed conversion rate; improve water quality and enhance immunity in aquaculture.

Lysozyme CAS 12650-88-3 safety

Safety: Certified as a safe food additive by FAO/WHO (1992); Non-toxic and has no side effects, does not damage human cells.

Storage:

Temperature: Store in a refrigerator at ≤ -20℃, protected from light, and avoid repeated freezing and thawing.

Stability: Long-term storage or in high temperature and high humidity environments will lead to a decrease in enzyme activity, and an increase in dosage is required for compensation.

Deshangchemical Info

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