L-Proline CAS 147-85-3 Information
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Chemical Name
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L-Proline
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Other Name
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Proline; α-Pyrrolidinecarboxylic acid
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CAS
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147-85-3
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EINECS
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205-702-2
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Type
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Food additives; Pharmaceutical raw materials; Organic raw materials; Pharmaceutical, pesticide and dye intermediates; Plant extracts
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Molecular Formula
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C5H9NO2
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Molecular Weight
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115.13
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L-Proline CAS 147-85-3 Properties
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Melting point
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228 °C (dec.) (lit.)
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alpha
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-85.5 º (c=4, H2O)
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Boiling point
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215.41°C (rough estimate)
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density
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1.35
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vapor pressure
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0Pa at 25℃
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refractive index
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-85 ° (C=4, H2O)
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storage temp.
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2-8°C
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solubility
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H2O: 50 mg/mL
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form
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powder
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pka
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1.95, 10.64(at 25℃)
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color
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White
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Odor
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at 100.00 %. odorless
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What is L-Proline CAS 147-85-3?
Under the common environmental conditions of normal temperature and pressure, L-proline presents in the form of white crystalline powder. Careful observation reveals that it has a slightly foul smell. Although this smell is not strong, it can be keenly detected. At the same time, it also has a hint of faint sweetness, giving people a unique taste experience.
This compound has a strong hygroscopicity. When it reacts with hydrated ninhydrin, it forms a bright yellow color. After undergoing the specific chemical treatment process of glacial acetic acid acidification, the original yellow color will gradually change back to red. This characteristic plays an important identifying role in related chemical experiments and analyses.
L-proline plays a crucial role in the life activities of the human body. It is one of the 20 amino acids in the human body and one of the indispensable important amino acids for the synthesis of human proteins. In the complex physiological metabolic process of the human body, the synthesis of proteins cannot do without the synergistic effect of various amino acids, and L-proline is a key link among them.
Not only that, L-proline is also an important raw material for amino acid infusion. In the medical field, amino acid infusion is of great significance for maintaining patients' nutritional balance and promoting physical recovery, and the stable supply of L-proline provides strong support for the production and quality assurance of amino acid infusion preparations.
In addition, in terms of drug synthesis, L-proline plays a crucial role even more. It is the main intermediate for the synthesis of first-line antihypertensive drugs such as captopril and enalapril. These antihypertensive drugs are widely used in clinical treatment and have significant therapeutic effects on controlling blood pressure in patients with hypertension and preventing complications of cardiovascular diseases. The high-quality supply of L-proline is directly related to the production quality and stability of these drugs.
With its unique chemical properties and important physiological functions, L-proline has been widely used in many industries such as food and medicine. In the food industry, it can be used as a food additive to improve the taste, flavor and nutritional value of food. In the pharmaceutical industry, apart from serving as an intermediate in drug synthesis and a raw material for amino acid infusion, it also demonstrates broad application prospects in multiple fields such as drug research and development and disease treatment.
According to relevant reports, L-proline is a component of many proteins. In living organisms, proteins are the basic substances that constitute the structure and function of cells and organisms. L-proline, as an important component of proteins, plays an irreplaceable role in maintaining the structure and function of proteins.
Meanwhile, L-proline is also widely present as a free acid in natural products. It can be detected in natural sources such as plants, animals and microorganisms. For example, in the extracts of some plants, the presence of L-proline may have important physiological significance for the growth and development, stress resistance and other aspects of plants.
It is worth mentioning that L-proline is the main component of collagen. Collagen, as the main fibrin in bones, cartilage and other connective tissues, plays a crucial role in maintaining the structural integrity, elasticity and toughness of the body. It is like a solid "scaffold", supporting all aspects of the body, and L-proline is one of the important construction materials of this "scaffold".
L-Proline CAS 147-85-3 Uses
L-proline, also known as proline, is one of the 18 basic amino acids that make up human proteins. At room temperature, it presents as anemia-like white crystals or crystalline powder and gives off a subtle smell. This substance is highly soluble in water, but insoluble in organic solvents such as ethanol, ether and n-butanol. Amino acids are a general term for a class of natural compounds containing amino and carboxyl groups, and they play a crucial role in living organisms.
First of all, amino acids, as key raw materials for protein synthesis, provide the necessary material basis for human growth and development, metabolism, and maintaining life activities. Secondly, L-proline, as a nutritional supplement, can be used as a raw material product for amino acid infusion, which helps to meet the human body's demand for specific amino acids. In addition, it has also been found to have the effect of lowering blood pressure, thus becoming an important intermediate component in the production of antihypertensive drugs on the front line, such as captopril and enalapril.
In family life, L-proline can also play its unique role. For instance, during the heating process, when it undergoes an amino acid carboxyl reaction with sugar, it can generate substances with a special aroma, adding a warm and cozy atmosphere to the home environment. Meanwhile, as a dietary supplement, L-proline can also enhance the cellular resistance of callus and increase its survival rate. In the field of agriculture, the appropriate addition of L-proline can alleviate the damage to the mitochondrial structure of regenerated rice plants caused by salt stress, thereby improving the growth quality of crops.
It is worth mentioning that proline and its by-products are often used as asymmetric catalysts in chemical catalytic reactions. For instance, in typical examples such as the CBS reduction reaction and the proline-militarized Aldo condensation reaction, they have demonstrated outstanding catalytic performance. In the brewing industry, the turbidity phenomenon caused by the combination of proline-rich healthy proteins and polyphenols is also an aspect worthy of attention.
Finally, due to the penetrating protective property of L-proline, it is widely used in the fields of pharmaceuticals and biotechnology. By adding it to the development tools used in the plant cell society, it can effectively promote plant growth and help plants better withstand the pressure brought by the tissue society.
