Isavuconazonium Sulfate cas 946075-13-4-Deshangchemical

Isavuconazonium Sulfate cas 946075-13-4

chem

------

English SynonymsIsavuconazon;BAL8557-002;N-Methylglycine[2-[[[1-[1-[(2R,3R)-3-[4-(4-cyanophenyl)-2-thiazolyl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-4H-1,2,4-triazolium-4-yl]ethoxy]carbonyl]methylamino]-3-pyridinyl]methylestersulfate(1:1);API-AntifungalInfection;savuconazoniumSulfate;EdoxabanFreeBas

CAS

946075-13-4

Molecular Formula

C35H36F2N8O9S2

Molecular weight

814.84

English Synonyms

Isavuconazon;BAL8557-002;N-Methylglycine[2-[[[1-[1-[(2R,3R)-3-[4-(4-cyanophenyl)-2-thiazolyl]-2-(2,5-difluorophenyl)-2-hydroxybutyl]-4H-1,2,4-triazolium-4-yl]ethoxy]carbonyl]methylamino]-3-pyridinyl]methylestersulfate(1:1);API-AntifungalInfection;savuconazoniumSulfate;EdoxabanFreeBase;ISAVUCONAZOLESULFATE;Isavuconazoniumsulfate(BAL8557)

Isavuconazole Sulfate Properties

Storage Condition	Store at -20°C
Solubility	Dmso: 93.34 (Maximum Concentration Mg/Ml); 114.55 (Maximum Concentration Mm) Dmso: Pbs (Ph 7.2) (1:5): 0.16 (Maximum Concentration Mg/Ml); 0.2 (Maximum Concentration. Mm) Ethanol: 10.0 (Maximum Concentration Mg/Ml); 12.27 (Maximum Concentration Mm)
Form	Crystalline Solid
Color	White to Off-White

Isavuconazole Sulfate Usage and Synthesis Method

New Antifungal Drugs

On March 6, 2015, The U.S. Fda Gave Priority Approval to Astellas; New Antifungal Drug Isavuconazonium Sulfate, Which Was Marketed Under the Trade Name Cresemba. It Is Used to Treat Invasive Aspergillosis and Mucormycosis, Two Fungal Infections That Are Common in Patients with Blood Cancer. Isavuconazonium Sulfate Is a Precursor Drug for Isavuconazole. After Entering the Body, It Is Metabolized into Isavuconazole and Exerts Its Antifungal Mechanism of Action. Isavuconazonium Sulfate Is Available in Oral and Injection Formulations. Isavuconazonium Sulfate Is Safer and More Effective Than Pfizer's Voriconazole (Vfend), And Has a Lower Mortality Rate.

Biological Activity

Isavuconazonium Sulfate (Bal8557-002) Is a Prodrug of the Active Triazole Antifungal Drug Isavuconazole and Is an Orally Active Antifungal Drug. Isavuconazonium Sulfate Is Used for Invasive Aspergillosis and Mucormycosis.

Whatsapp:+8613964085002

E-mail:info@deshangchem.com