Isavuconazole Intermediate 8 cas 368421-58-3

Isavuconazole Intermediate 8 cas 368421-58-3

chem

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English Synonyms(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide;NaMe:IsavuconazoleinterMediate8;(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)butanethioaMide;(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1

368421-58-3

C13H14F2N4OS

312.34

 

English Synonyms

(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMide;NaMe:IsavuconazoleinterMediate8;(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)butanethioaMide;(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamidehydrosulfatemonohydrate;Isavuconazoleintermediate8;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanethioamideHydrateHydrosulfate;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-Methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyraMid;Isavuconazoleintermediate8;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)thiobutyramide

Melting Point198-200°C
Boiling Point536.4±60.0 °C(Predicted)
Density1.43±0.1 g/cm3(Predicted)
Storage ConditionSealed in Dry,Room Temperature
SolubilitySoluble in Chloroform (A Little), Dmso (A Little), Methanol (A Little)
Acidity Coefficient (pKa)11.54±0.29(Predicted)
FormSolid
ColorOff White

Isavuconazole Intermediate 8 Usage and Synthesis Method

Use

Isavuconazole Intermediate Is an Intermediate in the Synthesis of Isavuconazole (I777830), A Triazole-Based Antifungal Agent Used to Treat Invasive Fungal Infections.

Application

Isavuconazole Intermediate 8 Is an Organic Synthesis Intermediate and a Pharmaceutical Intermediate, Which Can Be Used in Laboratory Research and Development Processes and Chemical Pharmaceutical Synthesis Processes.

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