Isavuconazole Impurities

English Synonyms

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanaMide;IsavuconazoleinterMediate6;(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanamide;(alphaR,betaR)-beta-(2,5-Difluorophenyl)-beta-hydroxy-alpha-methyl-1H-1,2,4-triazole-1-butanamide;4-triazole-1-butanaMide;1H-1,2,4-Triazole-1-butanamide,β-(2,5-difluorophenyl)-β-hydroxy-α-methyl-,(αR,βR)-;(alphaR,betaR)-beta-(2,5-Difluorophenyl)-beta-hydroxy-alpha-...;(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanaMide

Isavuconazole Intermediate 6 Properties

Isavuconazole Intermediate 6 Usage and Synthesis Method

Background

Isavuconazole, With a Molecular Formula of C22h17f2n5os, Is Usually Made into Isavuconazole Injection and Isavuconazole Capsules in the Pharmaceutical Field. It Belongs to the Azole Antifungal Drug Class and Targets the Cell Wall of Fungi. It Is Used to Treat Adult Patients with Invasive Aspergillosis and Invasive Mucormycosis. Isavuconazole Intermediate 6 Can Be Used to Synthesize Isavuconazole and Is the Main Intermediate in the Preparation of Apis.

Use

Isavuconazole Intermediate 6 (Formula 1), Namely 4-(2-((2r,3r)-3-(2,5-Difluorophenyl)-3-Hydroxy-4-(1h-1,2,4-Triazol-1-Yl)butane-2-Yl)thiazol-4-Yl)benzonitrile, Is a Key Intermediate in the Preparation of the Antifungal Drug Isavuconazole, And a Variety of Preparation Methods Have Been Disclosed.