English Synonyms
Deoxyursocholicacidmethylester;UrsodeoxycholicAcidEPImpurityG;(S)-methyl-4-((3S,5S,7S,8R,9R,10S,13R,14R,17S)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate;ChenodeoxycholicAcidEPImpurityG;ChenodeoxycholicAcidImpurity7;methyl(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate;UrsodeoxycholicAcidImpurity7（UrsodeoxycholicAcidEPImpurityG）;UrsodeoxycholicAcidEPImpurityG/UrsodeoxycholicAcidMethylEster/Methyl3,7-Dihydroxycholan-24-Oate
Deoxyursocholic Acid Methyl Ester Properties
| Melting Point | 142-143°C |
| Boiling Point | 507.6±25.0 °C(Predicted) |
| Density | 1.089±0.06 g/cm3(Predicted) |
| Storage Condition | Refrigerator |
| Solubility | Chloroform (Slightly Soluble), Ethanol (Slightly Soluble), Methanol (Slightly Soluble) |
| Acidity Coefficient (pKa) | 14.79±0.70(Predicted) |
| Form | Solid |
| Color | White to Off-White |
Usage and Synthesis of Deoxyursocholic Acid Methyl Ester
Overview
My Country Currently Adopts Artificial Breeding and Live Extraction of Udca, But It Has Many Steps, Long Cycles, And Low Yields, Which Cannot Meet Medical Requirements. Therefore, Artificial Synthesis of Udca Is of Great Significance. Since the 1950s, Many Chemical Synthesis Methods Have Been Tried. In the 1980s, Enzymatic Methods and Microbial Fermentation Methods Also Developed. At the Same Time, Chemical Synthesis Methods Have Also Seen Many Improvements, And There Is a Trend of Combining Enzymatic Methods, Fermentation Methods and Chemical Synthesis Methods to Prepare Udca.
Use
Ursodeoxycholic Acid (3α, 7β-Dihydroxy-5β-Cholanic Acid, Hereinafter Referred to as Udca) Is the Main Active Ingredient Contained in the Precious Chinese Medicine Bear Bile. It Is Clinically Used to Treat Various Gallstone Diseases and Various Acute and Chronic Liver Diseases with Good Results.
Ursodeoxycholic Acid Methyl Ester Is a Precursor for Making Udca (Ursodeoxycholic Acid), Which Plays an Important Role in Dissolving Cholesterol Gallstones and Promoting Fish Growth.
