DeoxyBenzoinOxime cas 952-06-7

DeoxyBenzoinOxime cas 952-06-7

chem

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English synonymsParecoxib Impurity 2;Benzyl phenyl ketoxime;NSC 135001;NSC 36666;SC-66276;α-Phenylacetophenone oxime;Ethanone,1,2-diphenyl-, oxime;(1E)-1,2-diphenylethanone oxiMe (Parecoxib sodiuM inteMediate)DeoxyBenzoinOxime PropertiesMelting point98℃Boiling Point375.4±21.0 °C(Predicted)Densit

952-06-7

C14H13NO

211.26

811-357-4

English synonyms

Parecoxib Impurity 2;Benzyl phenyl ketoxime;NSC 135001;NSC 36666;SC-66276;α-Phenylacetophenone oxime;Ethanone,1,2-diphenyl-, oxime;(1E)-1,2-diphenylethanone oxiMe (Parecoxib sodiuM inteMediate)

DeoxyBenzoinOxime Properties

Melting point98℃
Boiling Point375.4±21.0 °C(Predicted)
Density1.04±0.1 g/cm3 (20 ºC 760 Torr)
Acidity coefficient (pKa)11.07±0.11(Predicted)                

Overview

Parecoxib is a specific inhibitor of cyclooxygenase-2 (COX-2), a prodrug of valdecoxib, and a coxib analgesic in anti-arthritis drugs. Parecoxib is used for short-term treatment of postoperative pain. Clinically, the sodium salt of parecoxib is made into an injection. Diphenylacetophenone oxime is an intermediate for the preparation of parecoxib.

Uses

Diphenylacetophenone oxime is an organic compound, which is an intermediate for the preparation of parecoxib.


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