7-Fluoro-6-nitro-4-hydroxyquinazoline cas 162012-69-3-Deshangchemical

7-Fluoro-6-nitro-4-hydroxyquinazoline cas 162012-69-3

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English synonyms:7-FLUORO-6-NITRO-4-HYDROXY-QUINAZOLINE;7-FLUORO-6-NITROQUINAZOLINONE;7-Fluoro-6-Nitro-4(H)-Quinazoline;6-Nitro-7-Fluoro-4- HydroxyQuinazoline;7-fluoro-6-nitroquinazolin-4(1H)-one;7-Fluoro-6-nitro-1H-quina...;4(1H)-QUINAZOLINONE,7-FLUORO-6-NITRO-;7- fluoro-6-nitroquinazolin-4-o

CAS

162012-69-3

Molecular Formula

C8H4FN3O3

Molecular weight

209.13

EINECS

1308068-626-2

English synonyms:

7-FLUORO-6-NITRO-4-HYDROXY-QUINAZOLINE;7-FLUORO-6-NITROQUINAZOLINONE;7-Fluoro-6-Nitro-4(H)-Quinazoline;6-Nitro-7-Fluoro-4- HydroxyQuinazoline;7-fluoro-6-nitroquinazolin-4(1H)-one;7-Fluoro-6-nitro-1H-quina...;4(1H)-QUINAZOLINONE,7-FLUORO-6-NITRO-;7- fluoro-6-nitroquinazolin-4-ol

7-Fluoro-6-nitro-4-hydroxyquinazoline Properties：

Melting Point	282-285 °C(Solv: acetic acid (64-19-7))
Boiling Point	407.6±55.0 °C(Predicted)
Density	1.75±0.1 g/cm3(Predicted)
Storage conditions	Sealed in dry,Room Temperature
Solubility	Soluble in DMSO (a little), methanol (a little)
Form	Powder Crystal
Acidity coefficient (pKa)	-2.69±0.20(Predicted)
Color	Light yellow to yellow to orange

Usage:

7-Fluoro-6-nitroquinazoline-4(3H)-1 is an intermediate for the preparation of kinase inhibitors (such as ATP site inhibitors of the tyrosine kinase activity of epidermal growth factor receptor).

Usage:

7-fluoro-6-nitro-4-(hydrogen)-quinazolinone is an intermediate in organic synthesis and pharmaceutical research and development. It is also an anti-tumor drug intermediate and can be used to synthesize afatinib.

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