4-Chloro-3-fluoroaniline cas 367-22-6-Deshangchemical

4-Chloro-3-fluoroaniline cas 367-22-6

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English synonyms：4-Chloro-3-Fluoro-Phenylamine;4-Chloro-3-Fluoroaniline;3-Fluoro-4-Chloroaniline;buttpark44\01-97;4-Chloro-3-Fluorobenzenamine;4-Chloro-3-Fluoroanline;4- Chloro-3-Fluoroaniline98%;4-Chloro-3-Fluoroaniline98%4-Chloro-3-Fluoroaniline PropertiesMelting Point61Boiling Point226°C(lit.)D

CAS

367-22-6

Molecular Formula

C6H5ClFN

Molecular weight

145.56

EINECS

206-683-3

English synonyms：

4-Chloro-3-Fluoro-Phenylamine;4-Chloro-3-Fluoroaniline;3-Fluoro-4-Chloroaniline;buttpark44-97;4-Chloro-3-Fluorobenzenamine;4-Chloro-3-Fluoroanline;4- Chloro-3-Fluoroaniline98%;4-Chloro-3-Fluoroaniline98%4-

Chloro-3-Fluoroaniline Properties

Melting Point	61
Boiling Point	226°C(lit.)
Density	1.349±0.06 g/cm3(Predicted)
Flash point	60 - 62°C
Storage conditions	Keep in dark place,Inert atmosphere,Room temperature
Solubility	Soluble in methanol
Acidity coefficient (pKa)	2.94±0.10(Predicted)
Form	powder crystal
Color	white to gray to red
BRN	2716278

Usage:

4-chloro-3-fluoroaniline is used in the synthesis of 5-chloro-4-fluoro-1h-indole-2-carboxylic acid methyl ester; it is a key intermediate for HIV non-nucleoside reverse transcriptase phosphoindole inhibitors . 4-Chloro-3-fluoroaniline is also used in the synthesis of 3-dechloro-4-defluoro-4-chloro-3-fluorogefitinib, where it is an impurity in the tyrosine kinase inhibitor gefitinib.

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