4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE CAS 287930-73-8-Deshangchemical

4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE CAS 287930-73-8

chem

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English SynonymsAprepitantimpurity48;fosaprepitantimpurity23;4-Benzyl-2-Hydroxy-Morpholin-3-One;3-Morpholinone,2-Hydroxy-4-(Phenylmethyl)-;2-Hydroxy-4-(Phenylmethyl)-3-Morpholinone;fosaprepitantimpurityb;-2-Hydroxymorphol;aprepitantintermediates,4-Benzyl-2-Hydroxy-Morpholin-3-One4-Benzyl-2-hydroxy-m

CAS

287930-73-8

Molecular Formula

C11H13NO3

Molecular weight

207.23

EINECS

811-794-0

English Synonyms

Aprepitantimpurity48;fosaprepitantimpurity23;4-Benzyl-2-Hydroxy-Morpholin-3-One;3-Morpholinone,2-Hydroxy-4-(Phenylmethyl)-;2-Hydroxy-4-(Phenylmethyl)-3-Morpholinone;fosaprepitantimpurityb;-2-Hydroxymorphol;aprepitantintermediates,4-Benzyl-2-Hydroxy-Morpholin-3-One

4-Benzyl-2-hydroxy-morpholin-3-one Chemical Properties

Melting point	134.0 to 138.0 °C
Boiling Point	441.7±45.0 °C(Predicted)
Density	1.292±0.06 g/cm3(Predicted)
Storage conditions	Sealed in dry,Room Temperature
Solubility	Soluble in DMSO (slightly), methanol (slightly, heated)
Form	Solid
Acidity coefficient (pKa)	11.00±0.20(Predicted)
Color	White to off-white

Uses

Used to treat depression and chemotherapy-induced vomiting; can prevent acute and delayed nausea and vomiting caused by the first and subsequent repeated chemotherapy. API aprepitant/key intermediate of aprepitant

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