3,5-Dichloroaniline cas 626-43-7

3,5-Dichloroaniline cas 626-43-7

chem

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English Synonyms3,5-DCA;Phloroglucinol Impurity 26;3,5-dichloro;3,5-dichloro-anilin;3,5-dichloro-benzenamin;Aniline, 3,5-dichloro-;Benzenamine,3,5-dichloro-;BF352-313,5-Dichloroaniline PropertiesMelting Point46-52 °C (lit.)Boiling Point259-260 °C/741 mmHg (lit.)Density1.58Refractive Index1.6000 (e

626-43-7

C6H5Cl2N

162.02

 

English Synonyms

3,5-DCA;Phloroglucinol Impurity 26;3,5-dichloro;3,5-dichloro-anilin;3,5-dichloro-benzenamin;Aniline, 3,5-dichloro-;Benzenamine,3,5-dichloro-;BF352-31

3,5-Dichloroaniline Properties

Melting Point46-52 °C (lit.)
Boiling Point259-260 °C/741 mmHg (lit.)
Density1.58
Refractive Index1.6000 (estimate)
Flash Point>230 °F
Storage ConditionsStore Below +30°C.
SolubilitySolubility in Water 0.78 g/L
Acidity Coefficient (pKa)pK1:2.37(+1) (25°C)
FormCrystallization
ColorDark Gray

3,5-Dichloroaniline Uses and Synthesis Methods

Use

3,5-Dichloroaniline is an intermediate of the fungicides procymidone, iprodione, vinclozolin and sclerotin.

It is used as a raw material for agricultural pesticides. It can be used to produce diclozolin, sclerotin, vinclozolin, sclerotin, iprodione, fenclofen, cloflufenac and fenclofen. ; It can also be used to synthesize herbicides and plant growth regulators. It is used in the pharmaceutical industry to manufacture quinoline derivatives for the treatment of malaria. The dye industry is used in the manufacture of azo dyes and pigments. Used in industrial hygiene to manufacture pesticides and pest repellents.

Used as pesticides and pharmaceutical intermediates.

Oil intermediates. organic synthesis.

Production Method

1. 3,5-Dichloronitrobenzene hydrogenation method 2. Polychlorinated aniline dechlorination and hydrogenation method 3. Hydrogen iodide dechlorination method 4. Ammonolysis method consists of 1,3,5-trichlorobenzene (or 1,2, 4-Trichlorobenzene) is obtained by aminolysis. 5. Decarbonylation method is prepared by decarbonylation of 3,5-dichlorobenzamide. 6. The 2,6-dichloro-4-nitroaniline method uses 2,6-dichloro-4-nitroaniline as raw material, and is produced by diazotization and hydrogenation. 7. Acetanilide method uses acetanilide as raw material. After chlorination and hydrolysis, a mixture of 2,4 and 2,6-dichloroaniline is obtained. After bromination and diazotization, 3,5-dichloroaniline is obtained. Bromobenzene is then subjected to ammonolysis to obtain the product. 8. Obtained from p-nitroaniline (or o-nitroaniline) through chlorination, diazotization (deamination) and reduction. In addition, 3,5-dichloroaniline can also be produced from p-dichlorobenzene (or o-dichlorobenzene) through bromination, isomerization, and ammoniation.

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