Afatinib Impurities

English synonyms: 

4-QuinazolinaMine,N-(3-chloro-4-fluorophenyl)-6-amine-7-[[(3S)-tetrahydro-3-furanyl]oxy]-;6-Amino-4-[(3 -chloro-4-fluorophenyl)amino]-7-[[(S)-tetrahydro-3-furanyl]oxy]quinazoline;Afatinib-1;(S)-N4-(3-chloro-4-fluorophenyl)-7- (tetrahydrofuran-3-yloxy)quinazoline-4,6-diammine;4,6-Quinazolinediamine,N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]- ;Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl;N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4, 6-quinazolinediamine;Intermediatesofsunitinib

(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)quinazoline-4,6-diaMine Properties:

Introduction

N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furyl]oxy]-4,6-quinazolinediamine is a light yellow solid and can be used Used as pharmaceutical intermediates for pharmaceutical synthesis and experimental research.

use:

The quinazoline ring is an advantageous skeleton structure that can be combined with a variety of biological macromolecules to produce different biological activities. In particular, N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furyl]oxy]-4,6-quinazolinediamine is widely used in anti-tumor drugs. It is particularly prominent as an intermediate in synthesis. It is expected that breakthroughs will be made in the near future to develop highly efficient and low-toxic anticancer drugs through the overall design and optimization of the quinazoline ring in this molecule, which will contribute to human life and health.