Empagliflozin Impurities

English Synonyms

(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone;Methanone,(2-chloro-5-iodophenyl)(4-fluorophenyl)-;(2-Chloro-5-iodobenyl)(4-fluorophenyl)methanone;EmpagliflozinImpurity48;EnglenetImpurity16;2-chloro-4-fluoro-5-Iodobenzophenon;(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanon;2-Chloro-4'-fluoro-5-iodobenzophenone

(2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone Properties

Usage and Synthesis of (2-Chloro-5-iodophenyl)(4-fluorophenyl)ketone

Overview

(2-Chloro-5-Iodophenyl)(4-Fluorophenyl)methanone Is an Intermediate in the Synthesis of Empagliflozin. Empagliflozin Is a Sodium-Glucose Co-Transporter Type 2 Inhibitor Developed Jointly by Boehringer Ingelheim and Eli Lilly. Sglt-2 Inhibitors Are a New Type of Hypoglycemic Drug That Mainly Inhibits Sglt-2 Expressed in the Kidneys, Reduces Glucose Reabsorption by the Kidneys, And Increases Glucose Excretion in the Urine, Thereby Reducing Plasma Glucose Levels. Its Hypoglycemic Effect Is Independent of β-Cell Function and Insulin Resistance.