Empagliflozin Impurities

English Synonyms

2-CHLORO-4'-FLUOROBENZOPHENONE;2,4'-CFBP;2-Chloro-4'-fluorobenzophenone99%;2-Chloro-4'-fluorobenzophenone99%;4'-FLUORO-2-CHLOROBENZOPHENONE;(2-chlorophenyl)(4-fluorophenyl)-methanon;(2-Chlorophenyl)(4-fluorophenyl)methanone;2-Chloro-4'-fluorobe

2-Chloro-4'-Fluorobenzophenone Properties

Usage and Synthesis of 2-Chloro-4'-Fluorobenzophenone

Chemical Properties

2-Chloro-4'-Fluorobenzophenone Is a Colorless Solid with a Mp of 60-62°c. It Is Insoluble in Water but Soluble in Organic Solvents Such as Benzene, Toluene, And Ketone.

Use

2-Chloro-4'-Fluorobenzophenone Is an Intermediate of the Fungicide Fluphenazine.

Production Method

The Preparation Method Is to Place Fluorobenzene and Anhydrous Aluminum Chloride in a Reaction Kettle, Add 2-Chlorobenzoyl Chloride Dropwise at Low Temperature While Stirring, Raise the Temperature to Reflux After the Addition Is Complete, Continue the Reaction for Several Hours, Cool to Room Temperature, Add Hcl Dropwise, Control the Ph to 3-4, Separate the Layers, Dry the Oil Layer, And Distill to Obtain 4-Fluoro-2-Chlorobenzophenone.