Aprepitant Impurities

 

English Synonyms

(R,R,R)-Aprepitant;aprepitant Trans-1-Enantiomer;aprepitant Related Compound a (10mg)(3-[[(2r,3r)-2-[(R)-1-[3,5-Bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-Fluorophenyl)morpholino]methyl]-1h-1,2,4-Triazol-5(4h)-One);5-[[(2r,3r )-2-[(1r)-1-[3,5-Bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-Fluorophenyl)-4-Morpholinyl]methyl]-1,2-Dihydro-3h-1,2,4-Triazol-3-One;aprepitantrelatedcompounda;aprepitantepimpuritye;aprepitanta;aprepitantusprca(R,R,R-Diasteromer)

Aprepitant related substance A Properties

Density	1.51±0.1 g/cm3(Predicted)
Acidity coefficient (pKa)	8.06±0.20(Predicted)

Uses

Aprepitant-related substance A can be mainly used as a pharmaceutical reference substance.