Afatinib Impurities

English synonyms：

4-QuinazolinaMine,N-(3-chloro-4-fluorophenyl)-6-amine-7-[[(3S)-tetrahydro-3-furanyl]oxy]-;6-Amino-4-[(3-chloro- 4-fluorophenyl)amino]-7-[[(S)-tetrahydro-3-furanyl]oxy]quinazoline;Afatinib-1;(S)-N4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran- 3-yloxy)quinazoline-4,6-diammine;4,6-Quinazolinediamine,N4-(3-chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-;Afatinib- des(4-dimethylamino-2-en-1-oxo)butyl;N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine ;Intermediatesofsunitinib

Nature：

Introduction:

N4-(3-Chloro-4-Fluorophenyl)-7-[[(3s)-Tetrahydro-3-Furyl]oxy]-4,6-Quinazolinediamine Is a Light Yellow Solid and Can Be Used Used as Pharmaceutical Intermediates for Pharmaceutical Synthesis and Experimental Research.

Use:

The Quinazoline Ring Is an Advantageous Skeleton Structure That Can Be Combined with a Variety of Biological Macromolecules to Produce Different Biological Activities. In Particular, N4-(3-Chloro-4-Fluorophenyl)-7-[[(3s)-Tetrahydro-3-Furyl]oxy]-4,6-Quinazolinediamine Is Widely Used in Anti-Tumor Drugs. It Is Particularly Prominent as an Intermediate in Synthesis. It Is Expected That Breakthroughs Will Be Made in the near Future to Develop Highly Efficient and Low-Toxic Anticancer Drugs Through the Overall Design and Optimization of the Quinazoline Ring in This Molecule, Which Will Contribute to Human Life and Health.